The pathogenicity for mice of group B streptococci of bovine origin

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Presence of insertion sequences (IS elements) in group B streptococci of bovine origin.

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Deletion of repeats in the alpha C protein enhances the pathogenicity of group B streptococci in immune mice.

The alpha C protein is a protective surface-associated antigen of group B streptococci (GBS). The prototype alpha C protein of GBS (strain A909) contains nine identical tandem repeats, each comprising 82 amino acids, flanked by N- and C-terminal domains. Clinical isolates of GBS show variable numbers of repeats with a normal distribution and a median of 9 to 10 repeats. Here, we show that escap...

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ژورنال

عنوان ژورنال: Journal of Hygiene

سال: 1949

ISSN: 0022-1724

DOI: 10.1017/s0022172400014418